The primary aim is to facilitate an overall well-being for patients suffering from incurable neurological disorders through Neuroregenerative Rehabilitative Therapy (NRRT). In addition to the above, providing support to cellular therapy research & regenerative medicine and increasing awareness about its applications are supplementary objectives.
Some time ago donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: They can divide and replicate themselves as long as the person is alive.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. Read extra info at NeuroGen BSI.
Physical therapy is typically the first, and most important, step toward treating cerebral palsy. It usually begins at a young age and is geared toward improving independent motor function. The types of physical therapies used for children depend on their specific movement problems and symptoms that coincide with cerebral palsy. Before physical therapy begins, the therapist takes an assessment of the child’s motor capabilities. This helps determine the most appropriate measures for therapy. After evaluating the child, the therapist will prescribe strength training exercises, stretches and muscle relaxing techniques based on the child’s needs. Exercise equipment includes weights, resistance bands, balance balls and machines to improve muscle tone. Hot and cold packs are often used to help relax and heal muscles.
A few tips to help your child with autism: ADS support groups – Joining an ASD support group is a great way to meet other families dealing with the same challenges you are. Parents can share information, get advice, and lean on each other for emotional support. Just being around others in the same boat and sharing their experience can go a long way toward reducing the isolation many parents feel after receiving a child’s diagnosis. Respite care – Every parent needs a break now and again. And for parents coping with the added stress of ASD, this is especially true. In respite care, another caregiver takes over temporarily, giving you a break for a few hours, days, or even weeks. Individual, marital, or family counseling – If stress, anxiety, or depression is getting to you, you may want to see a therapist of your own. Therapy is a safe place where you can talk honestly about everything you’re feeling-the good, the bad, and the ugly. Marriage or family therapy can also help you work out problems that the challenges of life with an autistic child are causing in your spousal relationship or with other family members.
How do spinal cord injuries usually occur? A spinal cord injury is often the result of an unpredictable accident or violent event. The following can all result in damage to the spinal cord: a violent attack such as a stabbing or a gunshot, diving into water that’s too shallow and hitting the bottom, trauma during a car accident, specifically trauma to the face, head, and neck region, back, or chest area, falling from a significant height, head or spinal injuries during sporting events, electrical accidents, severe twisting of the middle portion of the torso.
Stem cells are an important area of ??current medicine due to their potential for regeneration and repair of the affected tissues. Some current therapies, such as bone marrow transplantation, are already using stem cells and their potential for regenerating damaged tissue. Other therapies are still under study and involve the transplantation of stem cells to an area of ??the body affected by the disease to direct them to develop and differentiate to create healthy tissue.
Muscular Dystrophy encompasses a group of genetic disorders which are characterised by progressive loss of muscle mass and subsequent weakness. Dystrophy is coined from the Greek word which essentially means ‘bad nourishment’. Early detection of muscular dystrophy started with a study by Sir Charles Bell, on the increasing weakness of the muscles of young boys, in 1830. This study on Muscular Dystrophy talks about a set of less than 30 genetic diseases that can lead to an alarming rate of increasing weakness of skeletal muscles applied through all voluntary movements. All these different ailments differ through the arrival stage, seriousness and prototype of muscles that are affected. All the manifestations of muscular dystrophy worsens as the muscles continually deteriorates and starts to weaken, and hence, it is considered as a “progressive muscular disorder”. Read extra details Stem Cell Therapy For Muscular Dystrophy.